YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)
ISSN 2383-9457 (ONLINE)
Signal detection of tocilizumab
| PRR | ROR | IC | signal | |
|---|---|---|---|---|
| Skin and appendages disorders | 1.70 | 1.94 | 0.34 | Y |
| Rash | 3.09 | 3.30 | 0.83 | Y |
| Pruritus | 2.26 | 2.37 | 0.46 | Y |
| Urticaria | 5.25 | 5.45 | 1.13 | Y |
| Rash erythematous | 5.15 | 5.21 | 0.64 | Y |
| Alopecia | 0.76 | 0.75 | -1.43 | |
| Body as a whole-general disorders | 1.13 | 1.15 | -0.25 | |
| Anaphylactic reaction | 50.99 | 52.49 | 1.99 | Y |
| Chest pain | 5.15 | 5.26 | 0.93 | Y |
| Fever | 1.22 | 1.23 | -0.67 | |
| Rigors | 4.12 | 4.15 | 0.36 | Y |
| Oedema peripheral | 1.64 | 1.64 | -0.61 | |
| Back pain | 5.56 | 5.60 | 0.45 | Y |
| Respiratory system disorders | 1.32 | 1.36 | -0.11 | |
| Dyspnoea | 2.94 | 3.01 | 0.51 | Y |
| Pharyngitis | 2.78 | 2.81 | 0.18 | Y |
| Pneumonia | 0.46 | 0.45 | -1.97 | |
| Coughing | 6.62 | 6.70 | 0.81 | Y |
| Upper respiratory tract infection | 0.90 | 0.90 | -1.21 | |
| Liver and biliary system disorders | 1.79 | 1.88 | 0.24 | Y |
| Hepatic enzymes increased | 5.33 | 5.61 | 1.24 | Y |
| SGPT increased | 1.24 | 1.24 | -0.84 | |
| SGOT increased | 1.00 | 1.00 | -1.08 | |
| White cell and RES* disorders | 1.59 | 1.64 | 0.04 | Y |
| Leucopenia | 6.42 | 6.69 | 1.31 | Y |
| Granulocytopenia | 0.59 | 0.58 | -1.59 |